Panacur
Anthelmintic - Active ingredient fenbendazole
The basic mechanism of the anthelmintic effect is inhibition of the polymerisation of tubulin into microtubules. This impairs important structural properties of the helminth cell, such as the formation of the cytoskeleton, spindle formation during mitosis and the uptake and intracellular transport of nutrients and metabolic substrates. As a result, the energy reserves are depleted, leading to the death of the parasite and its expulsion after 2 - 3 days.
It has an ovicidal effect, which occurs after approx. 8 hours as a result of disruption of spindle formation and metabolism during embryogenesis. It is highly effective against adult and immature gastrointestinal nematodes and lungworms, as well as against inhibited and acting larval stages. In addition, fenbendazole shows good efficacy against various tapeworm species.